Chemistry 330: Medicinal Chemistry (Spring 2018)

Course Description: This is a one-semester course in medicinal chemistry.  The first part of this course covers introduces students to the field of medicinal chemistry and covers fundamental topics and concepts relating to the properties, design, metabolism, and modeling of pharmaceutical drugs.  The remainder of the course is devoted to the major classes of therapeutic drugs with an emphasis on categorizing physiological effects with functional groups and binding site stereochemistry.  Laboratory provides students an introduction to computational modeling, experimental design, exploration of drug properties, and the synthesis and evaluation of biologically-active molecules.

Course Objectives:
1. Describe and apply the principles of medicinal chemistry
2. Understand drug metabolism and how it relates to drug design
3. Differentiate the basic classes of pharmaceuticals
4. Identify structure-function relationships for each drug class
5. Perform multi-step chemical synthesis of rationally-designed small molecules
6. Effectively demonstrate scientific writing (lab documentation, manuscripts, review articles)

Course Syllabus

Lecture Notes
**As lecture presentations contain copyrighted material from the textbook, access to these items is restricted to Augustana students enrolled in the course. Students can access these items through Moodle. An Augustana login and the course access code (obtained from Dr. Mays) is required.